I assume it's just not built to be fast, because it's still slow even with MySQL, Redis, high PHP memory limits, a fast CPU and NVMe storage, and so on.
Last time I tested it I had a load time of 1-2 seconds just to bring up the files interface, it feels laggy no matter what. And syncing a folder with ~50k files and 40GB or so in size takes a very long time compared to Syncthing or just syncing over SMB.
They're also useful because they're easy to deploy, contain all the dependencies needed, portable, and isolate things breaking from affecting the host or other containers.