Also you don't need that on arch /endevour. There are old nvidia drivers on the aur (I'm in the same situation than you and use those)
Potajito
I use endevour on my main PC but bazzite in the laptop, which I barely use, so I wanted something that didn't mind not updating for a month and be fine, and bazzite nails that. I use distrobox for terminal things and vpn software for work is layered. No issues so far and very tempted to run it in my main PC, probably would do that if when arch breaks.
Yeah no issues for me. Just ran the script to upgrade and reboot. All plugins are also working.
My client of choice! Nice!
I'd say distrobox is the easiest and safest way to do that.
Feishin for me and occasionally strawberry
I use a yubikey (couldn't chose, it's from work) and I have no issues with it working out of the box (endevour os). I just touch the "button" and it "types" the key.
Plus one for ublue images
Qt no doubt.
If you are in the fedora mood, try nobara os. It's fedora but with a spin on gaming, patches and some gui tools also. You can also try an inmutable distro like bazzite, which is also fedora and also focused on gaming. My advise would be to try a couple of things now that your system is clean and stick with whatever you like best.
Probably the web app works better than the native app. Also, try the flatpak if you still prefer native, it's better than what's on the repos imo.
Omv, that is debian with a Web interface basically