For me, it has been incredibly difficult to find a properly privacy oriented Linux distro that also has ease of use.
First of all, most distros already offer adequate privacy. It'll always beat Windows or MacOS—that's for sure.
Second, ease of use and privacy don't go hand in hand. The more privacy you want the harder it gets to use. The reason I emphasised privacy is because it's more anonymity at that point.
What is it you want? If it's privacy you're after you can't go wrong with most distros and using FOSS. If it's anonimity be prepared to make a ton of sacrifices. Have fun putting your laptop in a Faraday bag, routing all your traffic through Tor, visiting eepsites, disconnecting your webcam and microphone, only wiring money with Monero, and so forth.
My point is, there is no best of both worlds.
Worth every second