A mini PC could certainly work! If you're willing to go ebay, I'd recommend any of these Lenovo Thinkcentre SFF PCs:
https://forums.servethehome.com/index.php?threads/lenovo-thinkcentre-thinkstation-tiny-project-tinyminimicro-reference-thread.34925/
1-2x m.2 slots, 1x 2.5" slot, and some can accommodate a half-height PCI-E card in place of the 2.5" slot. Presumably, you'd want to go Intel for QSV
A mini PC could certainly work! If you're willing to go ebay, I'd recommend any of these Lenovo Thinkcentre SFF PCs:
https://forums.servethehome.com/index.php?threads/lenovo-thinkcentre-thinkstation-tiny-project-tinyminimicro-reference-thread.34925/
1-2x m.2 slots, 1x 2.5" slot, and some can accommodate a half-height PCI-E card in place of the 2.5" slot. Presumably, you'd want to go Intel for QSV