Not sure how technitium works but just from my selfhosting experience are you sure your not hitting dns-rebinding protection somwhere.
In short DNS rebinding stops domains from being resolved to private IP ranges so you don't end up back in your Network when you seem to be resolving a public domain.
I have to set up any domains that resolve locally in my router (which also does DNS and DHCP) but not sure if that's necessary with technitium
Still haven't properly set up my backups ... Have my Nextcloud on a zfs (single disk sadly) and want to send it to a server at my parents place (also zfs) but both are behind NAT. While I've successfully set up wireguard between the two, but the connection won't stay up so there's still a ways to go till I got a happy off-site Backup.