this post was submitted on 03 May 2026
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Absolutely 100% wrong.
In pancreatic ductal adenocarcinoma, a false positive means a follow-up scan. A false negative means death, the 5-year survival is near zero once it's caught late, but exceeds 80% when caught early.
In the study, the radiologists' lower false positive rate is achieved by missing 78% of cancers. That's not a safer trade-off, it's just a different way to fail. "Overdiagnosis" also requires a disease that might not have harmed the patient, PDA doesn't have a harmless form. Every missed case is a lost life while every false positive is an extra doctor's appointment.
This system detects twice as many cancers and was flagging them, on average, 675 days (nearly 2 years!) before clinical detection.
You selected a single pathology which supports your otherwise specious and false argument.
Be better.
Stop being a bad person, please.
If I'm wrong, then feel free to support your position with evidence or an argument showing that my statement was specious.
I linked the, peer-reviewed, paper which contains the data that supports my statements on the topic.
You've made two conclusory statements and immediately resorted to insulting comments when challenged.
There is not a single aggressive pancreatic cancer where a false negative is more dangerous than a false positive.
Percutaneous biopsy has a mortality rate of approximately 0.2% even relatively non-malignant pancreatic cancers (say Solid pseudopapillary neoplasm) have 10-year survival rates in adults of around 88% and that number is from cases which received surgical intervention and chemotherapy something that would not happen with a false negative.
So even in the worst case, the false negative multiple times more deadly. A false positives' most likely outcome is pancreatitis from the biopsy procedure.
They selected the pathology that’s the topic of the post to support their on-topic argument. Be better, indeed.
Really wish people could be better collaborators instead of just being jerks. Kills any value in the conversation.