There is no reason to use anonymous mode or disable those other options as long as your VPN is working correctly. Everything will be piped through the VPN connection and any peer or tracker will see the VPN server's IP, not yours.
The only thing I recommend doing is setting the network adapter in qbittorrent's advanced settings to the virtual one created by the VPN. This will ensure that no traffic accidentally goes through a non-VPN connection and exposes your IP.


