Sure. There's a rather vibrant writers' community, plenty of visual artists (including photography that isn't just cats and hiking), and the endless political shit.
You don't get as much of the random people running their mouths though.
The key to Mastodon is the # curation over time. Search your interests, use the hashtags to set up your feed, and only use the full federated feed to find terms you didn't think to search for, or that aren't obviously connected to your interests.
As an example, if you're a writer, you'll obviously follow something lunge #writing, but you might not find #pennedpossibilities, or #writerscoffeeclub by searching, despite them being active prompt based groups that end up having a lot of good interactions between writers (casual, amateurs, and pros).
Tbh, the least represented segment is the typically nerdy stuff. Much more prevalent on lemmy. There's plenty there, it just isn't as common as other segments.
I mean, we could also actually tear it down, but that's not going to happen, so I guess that's good advice.